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Exercise & Fitness
Fact: Regular physical activity - even at moderate levels - reduces the risk of heart disease, cancer, high blood pressure, and obesity. Here's another fact: 65% of Americans are considered obese. So while the risks associated with not exercising are clear, we don't seem to be doing anything to change our sedentary ways.




Prevention of Disease

The likelihood of contracting heart disease, diabetes, and other health issues can be directly impacted by our every-day choices. A good place to start for healthy lifestyle habits that can positively affect your health and wellness for years to come: 
1.Try reducing your stress levels. 
2. Adopt some stress-management techniques.
3. Focus on your emotional wellness.
Emotional health and well-being is just as important as physical health.
4. Supplement your diet with fresh vegetables and fruits and natural diet supplements from this website.



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IP6 May Cut Cancer 
Risk up to 70%



By Jose Antonio, Ph.D.

"This new cancer-fighter derived from fiber may also prove to be medicine for the new millennium."

The Facts

  • IP6 goes by the chemical name inositol hexaphosphate.
  • IP6 is basically a sugar molecule with phosphate groups attached.
  • IP6 has been shown to inhibit various cancers in humans and animals.
  • IP6 has been shown to be an effective treatment for kidney stones, high cholesterol and high blood lipids.
  • Much of the scientific support for IP6 is derived from the research of noted scientists Abulkalam Shamsuddin, M.D., of the University of Maryland School of Medicine.
  • Foods that contain significant amounts of IP6 include: soybeans, rice, sesame, beans, legumes, corn and cereals.
  • IP6 will soon be available over the counter.
  • IP6 has no known toxic effects.

This year, 564,800 Americans are expected to die of cancer. Although this number is alarming, the good news is that there are sound ways to prevent this nation's No. 2 killer. And, a recent discovery suggests a new natural treatment is on the horizon.

Research has long been espousing the benefits of soy in fighting cancer. Only recently, however, are we beginning to understand exactly why. Scientists have isolated a laundry list of soy constituents that suppress carcinogenesis including the Bowman-Birk inhibitor, beta sitosterol, and now, inositol hexaphosphate (IP6) or phytic acid.

Currently, there are a growing number of studies that support IP6's cancer-fighting properties. Additionally, IP6 has been shown to have potent antioxidant properties and to help treat kidney stones as well as high cholesterol and lipid levels.

What is it, and How Does it Work?

IP6, a ubiquitous substance found in virtually all mammals, is composed of the sugar inositol with six phosphate groups attached to it.

It is also an important component of cereals and legumes and may be the active ingredient in fiber that is anti-carcinogenic. The typical American diet is low in dietary fiber and relatively high in fat. It is not clear if the increased incidence of cancer is due to high fat intake, low fiber or both. Finland is one country in which the people tend to consume both a high-fat and high-fiber diet, and the risk of dying from breast cancer in Finnish women is lower than American women. Thus, it would seem that eating lots of fiber may be critical to preventing cancer.

What We Know Now

A study done by scientists at the University of Maryland School of Medicine in Baltimore examined whether a high-fiber diet reduced the amount of tumor cells in rats. Rats were divided into five groups and fed a diet that contained 0 percent, 5 percent, 10 percent or 20 percent Kellogg's All-Bran cereal; a fifth group received .4 percent IP6 in their drinking water; and amount equal to 20 percent bran. After 29 weeks, they found that in the 5 to 20 percent bran cereal groups, tumor incidence decreased 11 to 17 percent. Oddly enough, the rats that ate the least amount of bran had a lower tumor incidence than the group that ate the most bran. So from this, researchers could at least conclude that there was not a dose-response inhibition of the high-bran diet. This means that we may not need to stuff ourselves full of bran cereal in the morning in order to get the health benefits.

But what if we drank the IP6? Rats that were given IP6 in their water had an even lower incidence of tumor formation. In fact, drinking IP6 seemed to work twice as well as eating the high-bran foods.

IP6 has been introduced by mouth, by injection directly into tumors, intramuscular injection, intraperitoneal injection, etc. And regardless of how IP6 was given, it consistently had the same effects, whether it was tested on a colon-cancer model, a breast-cancer model, smooth-muscle cells, skeletal muscle tumors, liver cancers, etc.

In addition to animal studies, there are several human studies that have shown that IP6 inhibits growth of human prostate cancer cells and adenocarcinoma. Scientists have observed that cancer cells can revert back to normal cells in the presence of IP6. It should be pointed out that most of the research has been done with animals; in order for IP6 to gain greater support by the medical community, more human trials are needed.

One Scientist's Discovery

Abulkalam Shamsuddin, M.D., of the University of Maryland School of Medicine, is one of the leading authorities on IP6. He has an extensive scientific publication record on the topic of IP6. He reports his findings in his book IP6--Nature's Revolutionary Cancer Fighter (Kensington, 1998). According to Shamsuddin, the best evidence for the role of IP6 in fighting cancer is found in the comparison of cancer rates in Danish and Finnish populations. The fiber consumption of the Danes in nearly twice that of the Finns, yet the incidence of cancer in Danes is twice that of the Finns. This discovery suggests that the quality of fiber may be more important than the quantity of fiber consumed. Shamsuddin says, "The Finns actually eat a lot of porridge, which is where you have a lot of IP6... You see the Danes eat a lot of Fiber, and that fiber does not have IP6."

Where Can I Get IP6?

Most IP6 is derived from cereals. Corn apparently has the highest concentration of IP6 (~6 percent), followed by sesame (5 percent), wheat (2 to 3 percent) and rice (2 percent).

As of this printing, IP6 should now be available in pill or powder form. The advantage of taking a pill over food is that not all IP6 is absorbed from food. For instance, if you eat 100 gm of rice, not all of the 2 gm of IP6 present in that rice will be absorbed.

Although Shamsuddin admits that more research needs to be done before more specific dosage recommendations are given, he does provide the following guidelines. For prevention, a normal, healthy individual, should take 1 to 2 gm daily. Individuals with greater risk for cancer (due either to heredity predisposition or lifestyle factors), should take 4 gm daily as a preventive measure. If you want to make IP6 part of your treatment for cancer, take up to 8 gm daily (dose depends on stage of cancer).

Editor's note: Individuals should seek the guidance of their health-care practitioners in creating a preventive/treatment plan for cancer.

Any Possible Toxicity?

According to Shamsuddin, "There are no known harmful side effects of IP6." Suffice it to say that moderation seems to work well for most things in life, and certainly, IP6 is no different.

References

Shamsuddin, A.M. et al. "IP6: A Novel Anti-Cancer Agent," Life Sciences, 1997; 61:343-54.

Vucenik, I. et al., "Comparison of Pure Inositol Hexaphosphate and High-Bran Diet in the Prevention of DMBA-Induced Rat Mammary arcinogenesis," Nutrition and Cancer, 1997; 28:7-13.






**For your information: The products and the claims made about specific products on or through this site have not been evaluated by the United States Food and Drug Administration and are not intended to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.*



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