DIM (Di-Indolyl Methane), 60 caps, 200 mg
Cancer prevention by DIM (Di-Indolyl Methane) that increases
the good estrogen metabolites and decreases the bad estrogen
metabolites
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DIM
$29.95 60 caps
There is a remarkable increase in male
estrogen levels that occur with aging. High estrogen levels in
both men and women usually lead to cancer or other illnesses often
associated with aging, including prostate disease, breast and
uterine cancers, and weight gain.
Supplementing the diet with DIM and eating cruciferous
vegetables increases the specific aerobic metabolism for estrogen,
multiplying the chance for estrogen to be broken down into its
beneficial, or "good" estrogen metabolites. These
"good" estrogen metabolites are known as the 2-hydroxy
estrogens. Many of the benefits that are attributed to estrogen,
which include its ability to protect the heart and brain with its
antioxidant activity, are now known to come from these
"good" metabolites.
When DIM increases the "good" estrogen metabolites,
there is a simultaneous reduction in the levels of undesirable or
"bad" estrogen metabolites. These include the 16-hydroxy
estrogens, which are not antioxidants and can actually cause
cancer.
Greater production of these "bad" estrogen
metabolites is promoted by obesity and exposure to a number of
manmade environmental chemicals. These "bad" estrogen
metabolites are responsible for many of estrogen's undesirable
actions in women and men, including further unwanted weight gain,
breast cancer, uterine cancer, and prostate cancer.
DIM is highly recommended for women on HRT or at risk for
breast cancer as it will reduce the toxic effects to estrogen
dominance. "Regarding the ratio of 2-OH-estrone to
16-alpha-estrone, which is newer to me, I can inform you that a
poor 2/16 ratio (lower 2OH : higher 16-alpha) has been shown to be
carcinogenic. Extracts of cruciferous vegetables such as I3C
(indole-3-carbinole) and its more absorbable metabolite DIM (di-indolyl-methane)
apparently improve this ratio thru up-regulation of the CYP1A2
liver enzymes involved in the metabolism of estrogens (Cancer Lett
1997;114(1-2):169-170).
In fact, DIM has been shown to induce a favorable 2/16 ratio
and induce apoptosis in breast cancer cells (Biochem Pharmacol
1999; 58(5):825-34, Carcinogenesis 1998; 19(9):1631-9). In
addition, I3C also improved 2/16 ratios and induced a complete
regression in 50% of patients with cervical dysplasia of CIN
II-III (Gynecol Oncol 2000;78(2):123-9).
DIM may Prevent
Cervical Cancers and genital warts says Yale Researcher NIH
funds human trials at Yale Medical Center.
Price Comparison: Do not pay too much for DIM. LEF and
its affiliate Enzymatic Therapy charge $47.95 for 60 capsules, 120
mg. We manufacture the DIM ourselves and pass the savings on to you. Remember, this is a
supplement you take for a lifetime, so you need a good price.
Published clinical studies show adults need 200 mg of regular
DIM a day to be effective. No "absorption system" of any
kind is needed nor used in the scientific literature. Companies
who sell useless 75 mg doses with patented "absorption
systems" are just selling you an inferior product at an
inflated price.
INGREDIENTS
|
| Serving
Size : |
| Ingredient |
Quantity |
Measure |
RDA * |
| Di-Indolyl-Methane |
200 |
mg |
not
established |
|
* RDA means the Recommended Daily Allowance established by
the U.S. Food and Drug Administration. This is the minimum
daily amounts of specific essential nutrients necessary for
healthy adults 18 year of age. Requirements increase with
age and the RDA may be insufficient for older adults or
those with poor health |
|
