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IP6 - questions and answersDr Shamsuddin is Professor of medicine at the University of Maryland School of Medicine in Baltimore USA. Since 1975, he has been researching the process of cancer formation, cancer prevention and cancer treatment. He has pioneered the immune enhancing and anti-cancer actions of IP6 and inositol for which he was awarded the US & European patents. First performed in Dr. Shamsuddin's laboratory, experiments on the anti-cancer action of IP-6 and Inositol have been subsequently reproduced and extended by scientists around the world, reconfirming these fascinating findings. Inositol and IP-6, and the other inositol phosphates i.e. IP-1, IP-2, IP-3, IP-4, IP-5 are normally present in all mammalian cells. IP-3 is a key molecule responsible for cellular signal transduction, controlling vital functions including cell proliferation and differentiation. IP-6 can lose one or more phosphate (P) while inositol can gain them. Thus the combination of IP-6 and Inositol could yield more of the crucial IP-3. The theory is: since i) all cancers, irrespective of their type and origin have a common defect of uncontrolled cell proliferation, ii) IP-3 is a key regulator of cell growth and iii) IP-6 & Inositol yield IP-3, therefore, IP-6 & Inositol should be effective against many a different types of cancers, and across species. The proof can be seen in "About Us" and "What's New." Ongoing research are providing us with new information about these intriguing molecules, almost every day. The Author "IP6: Nature's Revolutionary Cancer Fighter", AbulKalam M. Shamsuddin, MD, PhD, is Professor of Pathology at the University of Maryland School of Medicine in Baltimore. Dr. Shamsuddin graduated from Dhaka Medical College in 1972. Following Internship in Massachusetts and Residency training in pathology in Maryland, he was certified by the American Board of Pathology in 1977. In 1980, he received Ph.D. degree from the University of Maryland for his work on colon carcinogenesis. He joined the faculty of the University of Maryland as an Instructor in 1977, and rose through the ranks of Assistant Professor and Associate Professor to become a full Professor in 1988. For his excellence in teaching, Professor Shamsuddin received the Best Teacher award from the medical students many times, including the coveted "Golden Apple Award" by the American Medical Students' Association in 1999. Dr. Shamsuddin's research on cancer started at the time he began his doctoral dissertation, in 1975. That work was based on his theory of "field effect phenomenon" and resulted in the subsequent invention of a very simple, accurate and practical mass screening test for cancers of the colorectum and lung with potential utility also for cancers of the breast, prostate, uterine cervix, etc. The colorectal cancer test is already popular in China where it is known as "Shams' Test." Dr. Shamsuddin's book on this subject, written for health care professionals is entitled Diagnostic Assays for Colon Cancer [CRC Press, Boca Raton, Florida 1991]. In mid 1985, Dr. Shamsuddin started his pioneering experiments on the anti-cancer property of inositol and inositol hexaphosphate (IP-6). |
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